If left untreated, detrusor external sphincter dyssynergia (DESD) can result in:

• Vesicoureteral reflux—Urine flowing backwards from the bladder to the urethra; may cause incontinence
• UTI—Upper and lower urinary tract infections
• Hydronephrosis—Enlargement of the kidneys and the renal pelvis (the structure that drains urine from the kidneys)
• Kidney stones—Occur when the urine has a high level of minerals that form stones
• Renal insufficiency or failure—Occurs when the filtering function of the kidneys change and they are no longer able to maintain healthy body function
• Due to these potentially severe consequences, urologists carefully manage patients with DESD so that excessive bladder pressures do not occur.